Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7z8r
Q-score: 0.573
Baek K, Scott DC, Henneberg LT, King MT, Mann M, Schulman BA
Cell (2023) 186 pp. 1895- [ DOI: doi:10.1016/j.cell.2023.02.035 Pubmed: 37028429 ]
- Cand1-cul1-rbx1 (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cullin-1 (89 kDa, Protein from Homo sapiens)
- Cullin-associated nedd8-dissociated protein 1 (137 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (12 kDa, Protein from Homo sapiens)
CAND1-SCF-SKP2 CAND1 engaged SCF rocked
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7z8t
Q-score: 0.488
Baek K, Scott DC, Henneberg LT, King MT, Mann M, Schulman BA
Cell (2023) 186 pp. 1895- [ DOI: doi:10.1016/j.cell.2023.02.035 Pubmed: 37028429 ]
- S-phase kinase-associated protein 2 (47 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cand1-scf-skp2 cand1 engaged scf rocked (Complex from Homo sapiens)
- Cullin-1 (89 kDa, Protein from Homo sapiens)
- Cullin-associated nedd8-dissociated protein 1 (137 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (12 kDa, Protein from Homo sapiens)
- S-phase kinase-associated protein 1 (18 kDa, Protein from Homo sapiens)
CAND1-SCF-SKP2 (SKP1deldel) CAND1 engaged SCF rocked
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 7z8v
Q-score: 0.523
Baek K, Scott DC, Henneberg LT, King MT, Mann M, Schulman BA
Cell (2023) 186 pp. 1895- [ DOI: doi:10.1016/j.cell.2023.02.035 Pubmed: 37028429 ]
- S-phase kinase-associated protein 2 (47 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cullin-1 (89 kDa, Protein from Homo sapiens)
- Cullin-associated nedd8-dissociated protein 1 (137 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (12 kDa, Protein from Homo sapiens)
- Cand1-scf-skp2 (skp1deldel) cand1 engaged scf rocked (Complex from Homo sapiens)
- S-phase kinase-associated protein 1 (16 kDa, Protein from Homo sapiens)
CAND1-SCF-SKP2 CAND1 rolling-2 SCF engaged
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7zbw
Q-score: 0.406
Baek K, Scott DC, Henneberg LT, King MT, Mann M, Schulman BA
Cell (2023) 186 pp. 1895- [ DOI: doi:10.1016/j.cell.2023.02.035 Pubmed: 37028429 ]
- S-phase kinase-associated protein 2 (47 kDa, Protein from Homo sapiens)
- Cand1-scf-skp2 cand1 rolling-2 scf engaged (Complex from Homo sapiens)
- Cullin-1 (89 kDa, Protein from Homo sapiens)
- Cullin-associated nedd8-dissociated protein 1 (137 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (12 kDa, Protein from Homo sapiens)
- S-phase kinase-associated protein 1 (18 kDa, Protein from Homo sapiens)
CAND1 delhairpin-SCF-SKP2 CAND1 partly engaged SCF partly rocked
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7zbz
Q-score: 0.494
Baek K, Scott DC, Henneberg LT, King MT, Mann M, Schulman BA
Cell (2023) 186 pp. 1895- [ DOI: doi:10.1016/j.cell.2023.02.035 Pubmed: 37028429 ]
- Cullin-associated nedd8-dissociated protein 1and s-phase kinase-associated protein 1 and 2 (Complex from Homo sapiens)
- S-phase kinase-associated protein 2 (47 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cullin-associated nedd8-dissociated protein 1 (137 kDa, Protein from Homo sapiens)
- Cullin-1 and e3 ubiquitin-protein ligase rbx1 (Complex from Homo sapiens)
- Cullin-1 (89 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1 (12 kDa, Protein from Homo sapiens)
- S-phase kinase-associated protein 1 (18 kDa, Protein from Homo sapiens)
- Cand1 delhairpin-scf-skp2 cand1 partly engaged scf partly rocked (Complex)
CAND1 b-hairpin++-SCF-SKP2 CAND1 rolling SCF engaged
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 8cdj
Q-score: 0.432
Baek K, Scott DC, Henneberg LT, King MT, Mann M, Schulman BA
Cell (2023) 186 pp. 1895- [ DOI: doi:10.1016/j.cell.2023.02.035 Pubmed: 37028429 ]
- Cullin-associated nedd8-dissociated protein 1 (137 kDa, Protein from Homo sapiens)
- S-phase kinase-associated protein 2 (47 kDa, Protein from Homo sapiens)
- Cand1 b-hairpin++-scf-skp2 cand1 rolling scf engaged (Complex from Homo sapiens)
- Cullin-1 (89 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (12 kDa, Protein from Homo sapiens)
- S-phase kinase-associated protein 1 (18 kDa, Protein from Homo sapiens)
CAND1 b-hairpin++-SCF-SKP2 CAND1 partly engaged SCF partly rocked
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 8cdk
Q-score: 0.473
Baek K, Scott DC, Henneberg LT, King MT, Mann M, Schulman BA
Cell (2023) 186 pp. 1895- [ DOI: doi:10.1016/j.cell.2023.02.035 Pubmed: 37028429 ]
- Cullin-associated nedd8-dissociated protein 1 (137 kDa, Protein from Homo sapiens)
- S-phase kinase-associated protein 2 (47 kDa, Protein from Homo sapiens)
- Cand1 b-hairpin++-scf-skp2 cand1 partly engaged scf partly rocked (Complex from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Cullin-1 (89 kDa, Protein from Homo sapiens)
- E3 ubiquitin-protein ligase rbx1, n-terminally processed (12 kDa, Protein from Homo sapiens)
- S-phase kinase-associated protein 1 (18 kDa, Protein from Homo sapiens)